Waters 717plus Manuel utilisateur

Artisan Technology Group is your source for quality

new and certied-used/pre-owned equipment

• FAST SHIPPING AND

DELIVERY

• TENS OF THOUSANDS OF

IN-STOCK ITEMS

• EQUIPMENT DEMOS

• HUNDREDS OF

MANUFACTURERS

SUPPORTED

• LEASING/MONTHLY

RENTALS

• ITAR CERTIFIED

SECURE ASSET SOLUTIONS

SERVICE CENTER REPAIRS

Experienced engineers and technicians on staff

at our full-service, in-house repair center

WE BUY USED EQUIPMENT

Sell your excess, underutilized, and idle used equipment

We also offer credit for buy-backs and trade-ins

www.artisantg.com/WeBuyEquipment

REMOTE INSPECTION

Remotely inspect equipment before purchasing with

our interactive website at www.instraview.com

LOOKING FOR MORE INFORMATION?

Visit us on the web at www.artisantg.com for more

information on price quotations, drivers, technical

specications, manuals, and documentation

View

Instra

Waters 717plus Autosampler

Operator’s Manual

34 Maple Street

Milford, MA 01757

173-02TP, Revision 2

Artisan Technology Group - Quality Instrumentation ... Guaranteed | (888) 88-SOURCE | www.artisantg.com

NOTICE

The information in this document is subject to change without notice and should not be

construed as a commitment by Waters Corporation. Waters Corporation assumes no

responsibility for any errors that may appear in this document. This manual is believed to

be complete and accurate at the time of publication. In no event shall Waters Corporation

be liable for incidental or consequential damages in connection with or arising from the

use of this manual.



1993 WATERS CORPORATION. PRINTED IN THE UNITED STATES OF AMERICA.

REPRODUCED IN ANY FORM WITHOUT THE WRITTEN PERMISSION OF THE

PUBLISHER.

LAC/E, PowerLine, and Waters are trademarks of Waters Corporation.

Millex is a trademark of Millipore Corporation.

Torx is a trademark of Camcar, Division of Textron, Inc.

The quality management systems of Waters manufacturing facilities comply with

the International Organization for Standardization International Standard ISO 9001

Quality Management and Quality Assurance Standards. Waters quality

management systems are periodically audited by the registering body to ensure

compliance.

Artisan Technology Group - Quality Instrumentation ... Guaranteed | (888) 88-SOURCE | www.artisantg.com

Attention:

The Waters 717plus Autosampler may be used for IN VITRO diagnostic

applications. This is a highly sensitive instrument. Read the accompanying operator's

manual before using.

When using the instrument, follow generally accepted procedures for quality control and

methods development.

If you observe a change in the retention of a particular compound, in the resolution

between two compounds, or in peak shape, immediately take steps to determine the

reason for the changes. Until you determine the cause of a change, do not rely upon the

results of the separations.

Attention:

Changes or modiﬁcations to this unit not expressly approved by the party

responsible for compliance could void the user’s authority to operate the equipment.

Attention:

This equipment has been tested and found to comply with the limits for a Class

A digital device, pursuant to Part 15 of the FCC rules.These limits are designed to provide

reasonable protection against harmful interference when the equipment is operated in a

commercial environment.This equipment generates, uses, and can radiate radio

frequency energy, and, if not installed and used in accordance with the instruction manual,

may cause harmful interference to radio communications.Operation of this equipment in a

residential area is likely to cause harmful interference, in which case you must correct the

interference at your own expense.

Shielded cables must be used with this unit to ensure compliance with the Class A FCC

limits.

Caution:

For continued protection against ﬁre hazard, replace fuses with those of the

same type and rating.

Caution:

To avoid the possibility of electric shock, do not remove the power supply covers.

The power supply does not contain user-serviceable components.

Attention:

To meet the regulatory requirements of immunity from external electrical

disturbances that may affect the performance of this instrument, do not use cables longer

than 9.8 feet (3 meters) when you make connections to the screw-type barrier terminal

strips. In addition, ensure you always connect the shield of the cable to chassis ground at

one instrument only.

The Installation Category (Overvoltage Category) for this instrument is Level II.The Level

II category pertains to equipment that receives its electrical power from a local level, such

as an electrical wall outlet.

STOP

Artisan Technology Group - Quality Instrumentation ... Guaranteed | (888) 88-SOURCE | www.artisantg.com

Canadian Emissions Notice

This digital apparatus does not exceed the Class A limits for radio noise

emissions from digital apparatus set forth in the Radio Interference

Regulations of the Canadian Department of Communications.

Le présent appareil numérique n’émet pas de bruits radioélectriques

dépassant les limites applicables aux appareils numériques de la classe A

prescrites dans les règlements sur le brouillage radioélectrique édictés par le

Ministère des Communications du Canada.

Symbols Used on 717plus Autosampler

Direct current

Alternating current

Protective conductor

terminal

Frame or chassis terminal

Caution, risk of electric

shock (high voltage)

Caution or refer to

manual

Artisan Technology Group - Quality Instrumentation ... Guaranteed | (888) 88-SOURCE | www.artisantg.com

Table of Contents 5

How to Use This Manual................................................................... 15

Chapter 1

Introduction ...................................................................................... 18

1.1 Description............................................................................ 18

1.2 Features................................................................................ 19

1.3 Components and Subsystems.............................................. 21

Chapter 2

Installation ....................................................................................... 23

2.1 Site Requirements ................................................................ 23

2.2 Unpacking and Inspection..................................................... 25

2.3 Changing Voltage Conﬁguration ........................................... 26

2.4 Connecting Fluid and Drain Lines ........................................ 29

2.5 Connecting Communication Cables ..................................... 32

2.5.1 Making Terminal Strip Connections........................... 33

2.5.2 Making IEEE-488 Network Connections.................... 39

2.5.3 Connecting RS-232 Output to Data Module.............. 40

2.6 Changing the Hardware Conﬁguration.................................. 41

2.6.1 Removing/Replacing the 717plus Cover.................... 41

2.6.2 Installing the Heater/Cooler....................................... 44

Table of Contents

Artisan Technology Group - Quality Instrumentation ... Guaranteed | (888) 88-SOURCE | www.artisantg.com

6 Table of Contents

2.6.3 Installing the Large Sample Loop.............................. 47

Chapter 3

Startup and Conﬁguration ................................................................ 50

3.1 Powering Up the Autosampler............................................... 50

3.2 Using the Front Panel ........................................................... 51

3.2.1 Accessing Menus....................................................... 52

3.2.2 Entering Operating Parameters................................. 54

3.3 Flushing the Autosampler ..................................................... 54

3.4 Calibrating the Seal Pak........................................................ 54

3.4.1 Purging the Autosampler........................................... 55

3.4.2 Auto Zeroing the Transducer...................................... 55

3.4.3 Calibrating the Seal Pak ............................................ 56

3.5 Priming the Needle Wash Pump........................................... 59

3.6 Conﬁguring the Autosampler ................................................ 60

3.6.1 Overview of Conﬁguration ......................................... 60

3.6.2 Setting Parameters for LC System Operation............ 63

3.6.3 Entering Hardware Changes ..................................... 67

3.7 System Veriﬁcation................................................................ 69

3.8 Power Down and Storage ..................................................... 70

3.8.1 Removing Buffered Mobile Phase ............................. 70

3.8.2 Powering Down.......................................................... 70

3.8.3 Storage...................................................................... 71

Artisan Technology Group - Quality Instrumentation ... Guaranteed | (888) 88-SOURCE | www.artisantg.com

Table of Contents 7

Chapter 4

Operating the Autosampler .............................................................. 72

4.1 Overview of Operation.......................................................... 72

4.2 Preparing Samples ............................................................... 74

4.2.1 Preparing Samples.................................................... 74

4.2.2 Selecting Sample Vials.............................................. 76

4.3 Selecting a Needle Wash Solvent......................................... 77

4.4 Loading the Carousel............................................................ 79

4.5 Ensuring Reproducibility....................................................... 81

4.5.1 Overview of Reproducibility....................................... 81

4.5.2 Performing a Purge.................................................... 81

4.5.3 Performing a Compression Check............................. 84

4.6 Running Autosampling.......................................................... 87

4.6.1 Programming Auto Run ............................................. 88

4.6.2 Programming Step Functions.................................... 92

4.6.3 Using Auto Standards ............................................... 94

4.6.4 Using Auto Addition .................................................. 99

4.6.5 Using Auto Transfer ................................................. 103

4.6.6 Programming the Event Output............................... 110

4.6.7 Starting and Stopping an Auto Run......................... 111

4.6.8 Monitoring Auto Run Status..................................... 112

4.7 Making a Stat Run .............................................................. 113

4.8 Sampling Considerations.................................................... 116

4.8.1 Temperature Control................................................ 116

4.8.2 Microbore/Semiprep Injections................................ 117

Artisan Technology Group - Quality Instrumentation ... Guaranteed | (888) 88-SOURCE | www.artisantg.com

8 Table of Contents

4.8.3 Injecting Viscous Samples ...................................... 120

4.8.4 Purging During an Auto Run.................................... 121

4.8.5 Using Buffered Mobile Phase.................................. 122

Chapter 5

Maintenance .................................................................................. 124

5.1 Defrosting the Heater/Cooler.............................................. 124

5.2 Replacing the Syringe......................................................... 126

5.2.1 Removing the Syringe ............................................. 126

5.2.2 Installing the New Syringe....................................... 129

5.3 Replacing the Seal Pak....................................................... 132

5.3.1 Removing the Injector.............................................. 133

5.3.2 Removing the Seal Pak ........................................... 134

5.3.3 Replacing the Needle .............................................. 135

5.3.4 Installing a New Seal Pak........................................ 136

5.3.5 Installing the Injector................................................ 137

5.3.6 Calibrating the Seal Pak .......................................... 137

5.4 Replacing In-Line Filters..................................................... 138

Chapter 6

Troubleshooting ............................................................................. 141

6.1 Safety and Handling............................................................ 141

6.2 Error Messages................................................................... 142

6.2.1 Informational Error Messages.................................. 143

6.2.2 Calibration (CAL) Error Messages........................... 143

Artisan Technology Group - Quality Instrumentation ... Guaranteed | (888) 88-SOURCE | www.artisantg.com

Table of Contents 9

6.2.3 Carousel (CAR) Error Messages............................. 144

6.2.4 Heater/Cooler (H/C) Error Messages ...................... 146

6.2.5 Injector (INJ) Error Messages.................................. 146

6.2.6 Syringe (SYR) Error Messages ............................... 147

6.3 Troubleshooting Tables........................................................ 147

6.4 Troubleshooting Procedures ............................................... 155

6.4.1 Manual Syringe Purge............................................. 155

6.4.2 Valve Leak Test........................................................ 156

6.4.3 Manual Transducer Adjustment ............................... 159

Appendix A

Speciﬁcations ................................................................................. 162

Appendix B

Spare Parts..................................................................................... 165

Appendix C

Warranty Information...................................................................... 169

C.1 Limited Product Warranty................................................... 169

C.2 Shipments, Damages, Claims, Returns.............................. 172

Appendix D

Reproducibility and Solvent Degassing.......................................... 174

D.1 Factors Affecting Reproducibility ........................................ 174

D.1.1 Chemical Factors Affecting Reproducibility............. 174

Artisan Technology Group - Quality Instrumentation ... Guaranteed | (888) 88-SOURCE | www.artisantg.com

Autres manuels pour 717plus

Table des matières

Autres manuels Waters Équipement de laboratoire

Waters

Waters 2707 Manuel

Waters

Waters ACQUITY UPLC M-Class Manuel de la liste des pièces

Waters

Waters ACQUITY UPLC Manuel d'utilisation

Waters

Waters Otto SPEcialist PPM Manuel d'utilisation

Waters

Waters Andrew+ Manuel utilisateur

Waters

Waters ACQUITY CM-30S Manuel d'utilisation

Waters

Waters Xevo TQD Manuel utilisateur

Waters

Waters Vion IMS QTof Manuel d'utilisation

Waters

Waters 2707 Manuel utilisateur

Waters

Waters ACQUITY Isocratic Solvent Manager Manuel d'utilisation

Waters

Waters Xevo TQ-S Manuel d'utilisation

Waters

Waters SYNAPT G2 Manuel utilisateur

Waters

Waters ACQUITY UPLC M-Class Manuel de la liste des pièces

Waters

Waters 2410 Manuel utilisateur

Waters

Waters TA Instruments Sample/Temperature Stage Manuel

Waters

Waters 717plus Manuel utilisateur

Waters

Waters Pipette+ Manuel utilisateur

Waters

Waters ACQUITY UPC2 Manuel de la liste des pièces

Waters

Waters Xevo TQD Manuel d'utilisation

Waters

Waters Andrew Alliance Magnet+ Manuel utilisateur

Waters

Waters Xevo TQD IVD Manuel d'utilisation

Waters

Waters Prep Series Manuel du produit

Waters

Waters Quattro Premier XE Manuel

Waters

Waters Extraction+ Manuel utilisateur

Manuels Équipement de laboratoire populaires d'autres marques

Qiagen

Qiagen DML 3000 Manuel utilisateur

Queensgate

Queensgate NANOSCAN OP400 Manuel de programmation

Conviron

Conviron GEN1000-GE Manuel utilisateur

Parr Instrument

Parr Instrument 4560 Mode d’emploi

IKA

IKA IC control Manuel utilisateur

Integra

Integra DOSE IT Manuel utilisateur

Agilent Technologies

Agilent Technologies 5800 ICP-OES Manuel utilisateur

Endress+Hauser

Endress+Hauser Cleanfit CPA875 Manuel utilisateur

NI PXI-5422 Manuel

Collomix

Collomix Aqix Manuel utilisateur

SPEX SamplePrep

SPEX SamplePrep 6875 Freezer/Mill Series Manuel utilisateur

Ocean Insight

Ocean Insight FLAME-NIR+ Manuel utilisateur

Parker

Parker ALIGN-MG-NA Manuel utilisateur

BD 644787 Manuel utilisateur

DENTAURUM

DENTAURUM Compact Megaplus Manuel utilisateur

Biuged Laboratory Instruments

Biuged Laboratory Instruments BGD 626 Manuel utilisateur

VWR

VWR SAS Super IAQ Manuel utilisateur

illumina

illumina MiSeqDx Manuel utilisateur