Molecular Devices ImageXpress Pico Manuel utilisateur

5063666 B

June 2018

ImageXpress®Pico

Automated Cell Imaging System

Installation Guide

ImageXpress Pico Personal Imaging System Installation Guide

2 5063666 B

This document is provided to customers who have purchased Molecular Devices equipment, software,

reagents, and consumables to use in the operation of such Molecular Devices equipment, software,

reagents, and consumables. This document is copyright protected and any reproduction of this

document, in whole or any part, is strictly prohibited, except as Molecular Devices may authorize in

writing.

Software that may be described in this document is furnished under a non-transferrable license. It is

against the law to copy, modify, or distribute the software on any medium, except as specifically

allowed in the license agreement. Furthermore, the license agreement may prohibit the software

from being disassembled, reverse engineered, or decompiled for any purpose.

Portions of this document may make reference to other manufacturers and/or their products, which

may contain parts whose names are registered as trademarks and/or function as trademarks of their

respective owners. Any such usage is intended only to designate those manufacturers’ products as

supplied by Molecular Devices for incorporation into its equipment and does not imply any right and/or

license to use or permit others to use such manufacturers’ and/or their product names as trademarks.

Each product is shipped with documentation stating specifications and other technical information.

Molecular Devices products are warranted to meet the stated specifications. Molecular Devices makes

no other warranties or representations express or implied, including but not limited to, the fitness of

this product for any particular purpose and assumes no responsibility or contingent liability, including

indirect or consequential damages, for any use to which the purchaser may put the equipment

described herein, or for any adverse circumstances arising therefrom. The sole obligation of Molecular

Devices and the customer's sole remedy are limited to repair or replacement of the product in the

event that the product fails to do as warranted.

For research use only. Not for use in diagnostic procedures.

The trademarks mentioned herein are the property of Molecular Devices, LLC or their respective owners. These trademarks may not

be used in any type of promotion or advertising without the prior written permission of Molecular Devices, LLC.

Patents: http://www.moleculardevices.com/patents

Product manufactured by Molecular Devices, LLC.

3860 N. First Street, San Jose, California, 95134, United States of America.

Molecular Devices, LLC is ISO 9001 registered.

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Contents

Safety Information 5

Warnings, Cautions, Notes, and Tips 5

Symbols on Instrument Labels 6

Before Operating the Instrument 7

Protective Housing 7

Electrical Safety 8

Moving Parts Safety 9

Lifting Hazard 10

Chemical and Biological Safety 10

Cleaning and Maintenance 11

Chapter 1: ImageXpressPicoAutomated Cell Imaging System 13

ImageXpressPico System Features 14

CellReporterXpress Software Features 16

Theory of Operation 17

Obtaining Support 20

Product Documentation 22

About This Guide 22

Chapter 2: Setting Up the ImageXpressPico System 23

Package Contents 23

Unpacking the Instrument 24

Placing the Instrument 26

Removing the Transport Lock 26

Connecting Cables 27

Powering On the Instrument 29

Chapter 3: Installing the CellReporterXpress Software 31

Chapter 4: Finishing Setup of the ImageXpressPico System 33

Logging In to the Software 33

Installing a Filter Cube 34

Installing an Objective 36

Inserting the Plate Holder or Slide Holder 38

ImageXpress Pico Personal Imaging System Installation Guide

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Appendix A: Instrument Specifications 41

Instrument Dimensions 43

Appendix B: Compatible Objectives 47

Appendix C: Filter Cube Specifications 49

Appendix D: Replacement Parts and Optional Extras 51

Appendix E: Packing the Instrument for Transport 53

Appendix F: Electromagnetic Compatibility 57

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Safety Information

The safety information section provides information on the safe use of the instrument. It

includes the use of user-attention statements in this guide, a key to understanding the

safety labels on the instrument, precautions to follow before operating the instrument, and

precautions to follow while operating the instrument.

Read and observe all warnings, cautions, and instructions. Remember, the most important

key to safety is to operate the instrument with care.

WARNING! If the instrument is used in a manner not specified by Molecular

Devices, the protection provided by the equipment might be impaired.

Warnings, Cautions, Notes, and Tips

All warning symbols in the user guide are framed within a yellow triangle. An exclamation

mark is used for most warnings. Other symbols can warn of other types of hazards such as

biohazard, electrical, or laser safety warnings as are described in the text of the warning.

When warnings and cautions are displayed in this guide, be careful to follow the specific

safety information related to them.

The following user-attention statements can be displayed in the text of Molecular Devices

user documentation. Each statement implies a particular amount of observation or

recommended procedure as described:

WARNING! A warning indicates a situation or operation that could cause

personal injury if precautions are not followed. The warning symbol can vary

depending on the warning. The definition of the symbol is included in the text of

the warning.

CAUTION! A caution indicates a situation or operation that could cause damage to

the instrument or loss of data if correct procedures are not followed.

Note: A note calls attention to significant information.

Tip: A tip provides useful information or a shortcut, but is not essential to the

completion of a procedure.

ImageXpress Pico Personal Imaging System Installation Guide

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Symbols on Instrument Labels

Each safety label found on the instrument contains an alert symbol that indicates the type of

potential safety hazard related to the label. The following table lists the alert symbols that

can be found on Molecular Devices instruments.

Symbol Indication

Indicates that the product documentation must be consulted.

Indicates a potential lifting hazard. For information about the weight of the instrument,

Indicates a potential heat hazard.

Indicates a rotating parts hazard.

Indicates the location of a fuse.

Indicates the instrument serial number.

Indicates the instrument manufacture date.

Indicates that you should consult the instructions for use.

Indicates CSA certification.

Indicates European technology conformity.

Safety Information

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Symbol Indication

Indicates compliance with Australian radio communication requirements.

This symbol on the product is required in accordance with the Waste Electrical and

Electronic Equipment (WEEE) Directive of the European Union. It indicates that you

must not discard this electrical or electronic product or its components in domestic

household waste or in the municipal waste collection system.

For products under the requirement of the WEEE directive, contact your dealer or

local Molecular Devices office for the procedures to facilitate the proper collection,

treatment, recovery, recycling, and safe disposal of the device.

Indicates the environmental friendly use period.

Indicates that there is an authorized representative in the European community.

Indicates the instrument manufacturer.

Indicates the manufacturer catalog number.

Before Operating the Instrument

Make sure that everyone involved with the operation of the instrument has:

Received instruction in general safety practices for laboratories.

Received instruction in specific safety practices for the instrument.

Read and understood all Safety Data Sheets (SDS) for all materials being used.

Protective Housing

The instrument features a protective outer housing, which is designed to protect you from

exposure to LED light, hot surfaces, and moving parts.

WARNING! Do not manually open the plate door, open the protective housing,

or attempt to gain access to the interior of the instrument. These actions can

damage the instrument components and result in hazardous exposure to LED light,

hot surfaces, moving parts, or high voltage.

ImageXpress Pico Personal Imaging System Installation Guide

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Electrical Safety

To prevent electrically related injuries and property damage, inspect all electrical equipment

before use and immediately report all electrical deficiencies. Contact Molecular Devices

Technical Support to service equipment that requires the removal of covers or panels.

WARNING! HIGH VOLTAGE. Within the instrument is the potential of an

electrical shock hazard existing from a high-voltage source. Read and understand

all safety instructions before you install, maintain, or service the instrument.

Do not remove the instrument covers. To prevent electrical shock, use the supplied power

cords only and connect to a properly grounded wall outlet.

To ensure sufficient ventilation and provide access for disconnecting power from the

instrument, maintain a 20 cm to 30 cm (7.9 in. to 11.8 in.) gap between the rear of the

instrument and the wall.

Power off the instrument when not in use.

If the instrument does not power on, you may need to replace the instrument fuses. See

Replacing Fuses on page 8 for details.

Replacing Fuses

If the instrument does not seem to get power after you press the Power button, confirm

that the power cord is securely connected to a functioning power outlet and to the power

port on the rear of the instrument.

If the power failed while the instrument was running, verify that the power cord is not loose

or disconnected and that power to the power outlet is functioning properly.

If these checks fail to remedy the loss of power, replace the fuses. You can obtain

replacement fuses from Molecular Devices. See Replacement Parts and Optional Extras on

page 51 for details on fuse specifications and part numbers.

CAUTION! Do not touch or loosen screws or parts other than those specifically

designated in the instructions. Doing so could cause misalignment and possibly void

the warranty.

The fuses are located in the fuse carrier which is part of the power outlet on the rear of the

instrument.

Safety Information

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WARNING! HIGH VOLTAGE Always power off the instrument and disconnect the

power cord from the main power source before you perform a maintenance

procedure that requires removal of a panel or cover or disassembly of an interior

instrument component.

To replace fuses:

1. Press and hold the Power button to power off the instrument.

2. Disconnect the power cord from the power port.

3. Use a small flat-head screwdriver to gently press on the carrier-release tab and then pull

the fuse carrier to remove it from the instrument.

4. Gently pull the old fuses from the carrier by hand.

5. Gently place the new fuses into the carrier.

6. Press the fuse carrier into the instrument until the carrier snaps into place.

7. Connect the power cord into the power port.

8. Press the Power button to power on the instrument.

Note: If the instrument still does not power on after you change the fuses, contact

Molecular Devices Technical Support. See Obtaining Support on page 20 for details.

Moving Parts Safety

The instrument contains moving parts that can cause injury. Under normal conditions, the

instrument is designed to protect you from these moving parts.

To prevent injury:

Never try to exchange labware, reagents, or tools while the instrument is operating.

Never try to physically restrict the moving components of the instrument.

WARNING! Do not attempt to access the interior of the instrument unless

specifically instructed to do so. The moving parts inside the instrument can cause

injury. Do not operate the instrument with any covers or panels removed.

Note: Observe all warnings and cautions listed for all external devices attached to or in

use during the operation of the instrument. See the applicable user guide for the

operating and safety procedures of that device.

ImageXpress Pico Personal Imaging System Installation Guide

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Lifting Hazard

WARNING! LIFTING HAZARD The ImageXpressPico System weighs

approximately 38 kg (84lb.). Use great care when lifting or moving the

instrument. To prevent injury, use a minimum of two people to lift the

instrument.

CAUTION! Moving the instrument can damage sensitize parts and disrupt optical

alignments. When transporting the instrument, use the original packaging and

shipping box to properly secure the instrument. Your warranty does not cover

problems caused during or as a result of shipment or relocation.

Chemical and Biological Safety

Normal operation of the instrument can involve the use of materials that are toxic,

flammable, or otherwise biologically harmful. When using such materials, observe the

following precautions:

Handle infectious samples based on good laboratory procedures and methods to

prevent the spread of disease.

Observe all cautionary information printed on the original containers of solutions before

their use.

Dispose of all waste solutions based on the waste disposal procedures of your facility.

Operate the instrument in accordance with the instructions outlined in this guide, and

take all the required precautions when using pathological, toxic, or radioactive materials.

Splashing of liquids can occur. Therefore, take applicable safety precautions, such as

using safety glasses and wearing protective clothing, when working with potentially

hazardous liquids.

Observe the applicable cautionary procedures as defined by your safety officer when

using hazardous materials.

Observe the applicable cautionary procedures as defined by your safety officer when

using flammable solvents in or near a powered-up instrument.

Observe the applicable cautionary procedures as defined by your safety officer when

using toxic, pathological, or radioactive materials.

WARNING! Never use the instrument in an environment where potentially

damaging liquids or gases are present.

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