BioFluidix BioSpot BT600 Manuel utilisateur

BioFluidix GmbH

Engesserstraße 4a

D-79108 Freiburg, Germany

www.biofluidix.com

User Manual

BioSpot BT600

Version: 1.1

Date: March 2018

Manual - BioSpot BT600 workstation

page 1 of 15

Before operating the unit,

please read this manual thoroughly

and retain it for future reference

Content

1. Safety Instructions ....................................................................................................... 2

1.1 Electrical Safety .......................................................................................................... 2

1.2 Mechanical Safety ...................................................................................................... 3

1.3 Chemical safety .......................................................................................................... 3

1.4 Intended use............................................................................................................... 4

1.5 Reasonably foreseeable misuse................................................................................. 4

2. Unpacking and transport ............................................................................................. 5

3. Installation of the BioSpot BT600................................................................................. 5

4. List of parts .................................................................................................................. 5

5. Description of the BioSpot BT600................................................................................. 6

5.1 BioSpot BT600 workstation........................................................................................ 6

5.2 Connectors at the control electronics located at the z-axisFehler! Textmarke nicht

definiert.

5.3 Backside connectors (integrated PC) ......................................................................... 8

5.4 Print heads and dispensers (can be ordered separately) .......................................... 8

5.5 Accessories (can be ordered separately) ................................................................... 8

6. Operating the BioSpot BT600..................................................................................... 10

6.1 Start up ..................................................................................................................... 10

6.2 Switching off............................................................................................................. 11

7. Appendix ................................................................................................................... 12

7.1 Basic settings ............................................................................................................ 12

7.2 Interfaces.................................................................................................................. 12

7.3 Technical data .......................................................................................................... 13

7.4 Dimensions ............................................................................................................... 13

7.5 Maintenance and repair........................................................................................... 14

7.6 Disposal .................................................................................................................... 14

8. Revision history ......................................................................................................... 14

9. Contact ...................................................................................................................... 15

Manual - BioSpot BT600 workstation

page 2 of 15

1. Safety Instructions

Read the safety instructions first, before operating the system!

We will take no liability in case of material or person damage, due to incorrect use or inobservance of

the manual respectively the safety instructions. In this case, every warranty claim expires.

•Avoid operation in contrarious environmental conditions. This may lead to damage to the

electronics and to a possible hazard for the health of the user.

Contrarious environmental conditions are:

-Too high humidity (greater than 80%, condensing)

-Moistness

-Too high environmental temperature (more than 45°C)

•Only put the BioSpot BT 600 in operation if the device is located on a stable and flat base and

there are no visible damages like isolation damages on cables or damages on mechanical

parts.

•If it is supposed, that it is not possible to launch a safe operation, you have to take it out of

service and protect it against an unintended operation. It is supposed, that an safe operation

is not possible if:

-the BioSpot BT600 shows visible damages,

-the BioSpot BT600 isn´t working and

-after a longer storage in bad conditions or

-after heavy load due to transport.

1.1 Electrical Safety

Warning!

High voltage hazard

Do not open the BioSpot BT600! The device contains circuits which carry power supply voltage.

Opening is only allowed to skilled personnel while the power plug is disconnected. Inadmissible

operations will nullify the warranty!

Service and maintenance of the BioSpot BT600 may only be executed by skilled personal!

Warning:

High voltage hazard after switching off the device!

CAUTION: After switching off the device, a DC voltage of 180 V remains in the circuits for several

minutes due to a capacitance in the circuits!

Manual - BioSpot BT600 workstation

page 3 of 15

Warning:

High voltage hazard at plugs and sockets!

All power supply connectors as well as the connectors for the dispensers or print heads need to be

considered as points of possible danger in kind of high voltage! Switch off the device before changing

any connection! Do not touch any plug or socked during operation.

1.2 Mechanical Safety

Warning:

Danger of injury by moving parts!

The installation of the BioSpot BT600 device requires free space surrounding the device to enable a

free movement of all moving axes!

Prevent the entrance of any foreign object as liquids or screws into the BioSpot BT600 device.

It is prohibited to store or place any object on the platen of the BioSpot BT600 which is not in the

purpose of use. Keep your hands away from all moving elements during operation.

Warning:

Finger or hand injury!

Don’t touch any moving parts during operation. In case of need, the movement can immediately be

stopped by pressing the red emergency switch on the right side!

Load or unload the device only if the machine is in a wait position!

1.3 Chemical safety

Warning:

Danger of fire and explosion!

Do not use or clean the device with flammable or chemical aggressive media or solvents. Always

wear protective gloves, eye protection and lab coat when operating the device. Always consult the

safety data sheets of the liquids used for dispensing and ensure that the required safety measures

are taken.

Manual - BioSpot BT600 workstation

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1.4 Intended use

The BioSpot BT600 workstation (complete machine) is intended to be used accordingly to the

installed components. This means that the designated use, with respect to the Machinery Directive

(published by the European Commission in 2006, section 1.1.2) is generally defined by the installed

components (e.g. PipeJet dispenser).

Considering this premise, the BioSpot BT600 may be applied for dosing liquids, coating surfaces, to

measure two dimensional geometries or for aspirating liquids.

The BioSpot BT600 workstation is intended for the following uses considering following guidelines:

•positioning of print heads and dosing units which are authorized to be used with

the system by BioFluidix

•the BioSpot BT600 is intended for indoor use in a laboratory or industrial

environment only

•the BioSpot BT600 is to be operated by skilled personnel who are familiar with

the user’s manual only.

The BioSpot BT600 workstation without installed components (incomplete machine) may be

extended to a complete machine by the customer, when adding any of the authorized components

(please contact BioFluidix) to a complete machine. Thereby, the customer needs to follow the

currently effective Machinery Directive. Furthermore, the customer is in this case responsible for

certificating the final device in purpose of own use or distribution.

Other use as listed is not allowed and will lead to damage of the BioSpot BT600. The whole product

may not be changed or reconstructed.

1.5 Reasonably foreseeable misuse

•Use of non-authorized print heads or dispensers

•Installation and use of different tools or components

•Use of harmful or dangerous liquids

•Applications which are not following the declaration of conformity

•Operation by non-skilled personnel

Manual - BioSpot BT600 workstation

page 5 of 15

2. Unpacking and transport

For unpacking the BioSpot BT600 workstation a minimum of two persons are required. Don’t lift the

BioSpot at the z-axis or any plastic housing or surface. Lift the BioSpot by grapping the lower profile

in close proximity to the system support feet solely.

Before unpacking the BioSpot BT600 from the box, remove all additional parts from the box.

Store all packing material for later movement or transports of the BioSpot system.

3. Installation of the BioSpot BT600

It is strongly prohibited to operate the device in outdoor environment. Use the device indoors in

clean and dry environment. The installation base needs to offer a stationary, even and robust

surface. It must resist the appearing acceleration forces during operation. It is essential to ensure

that no components, devices, etc. might collide with the movable parts of the BioSpot BT600 during

operation. CONSIDER: some parts might extend the borders of the system during operation!

4. List of parts

Please make sure that the following items are part of your BioSpot BT600 system. If any items are

missing please contact BioFluidix immediately.

CONSIDER:Print heads, dispensers or other components must be ordered separately and are not

part of the BioSpot BT600 workstation!

BioSpot BT600 workstation power supply connectors keyboard/mouse

Manual - BioSpot BT600 workstation

page 6 of 15

5. Description of the BioSpot BT600

The BioSpot BT600 is a laboratory robot enabling the positioning of print heads or dispensers

authorized by BioFluidix GmbH. According to the intended configuration, the BioSpot BT600 can be

applied as pipetting or dispensing unit for non-contact dosage applications of liquids.

5.1 BioSpot BT600 workstation

Figure 1: Photograph of the BioSpot BT600 workstation indicating the most important functional parts

Dispenser connection

Plug/socket to connect a dispenser, e.g. up to eight PipeJet dispensers

Warning:

High voltage hazard at plugs and sockets!

Dispenser mount

mechanical adaption for dispensers or other printheads

deck plate

working area/ surface of the BioSpot BT600 to position the desired substrates

(costumer specifically designed. May feature different holder structures for microscope slides

or micro well plates)

power LED (green)

Status LEDs

Deck plate

Dispensers

SmartDrop

Emergency switch

Manual - BioSpot BT600 workstation

page 7 of 15

indication for power supply (illuminates while the BioSpot BT600 is switched on and

connected correctly to the power supply)

dispense LED red/ yellow

indication for a dosing event (illuminates at each dispense)

move LED blue

indication for axes movement (illuminates while any axis x/y/z is moving)

power toggle switch (back side)

enables the power supply of the BioSpot BT600. Using this switch supplies all components

with power, including PC and dosing electronics.

emergency switch

Pressing the emergency switch disconnects all internal components from the power supply,

except the internal PC and the power switch on the back side. The emergency switch can be

used to stop non-intended movement of one of the axis or non-intended dosage.

PLEASE NOTE:

After using the emergency switch, the axes need to be re-referenced!

Further, it is required to re-boot the internal PC after pressing the emergency switch in order

to put the BioSpot back into operation.

Dispenser connection

Connector sockets for up to 8 PipeJet dispenser units; U = 0 to 180V

Warning:

High voltage hazard at plugs and sockets!

USB connector

Standard USB 2.0 connector, intended for the connection of a TopView camera

(may be ordered separately)

Connection for ring-light

Current controlled connector for the TopView camera illumination

(may be ordered separately)

Manual - BioSpot BT600 workstation

page 8 of 15

5.2 Backside connectors (integrated PC)

Figure 2: Photograph of the backside connectors (integrated PC)

RJ 45/ Ethernet connection

LAN connector

USB connection

intended to connect mouse and keyboard

DVI connection

intended to connect a screen

5.3 Print heads and dispensers (can be ordered separately)

The BioSpot BT600 is able to operate different printheads or dosing units authorized by

BioFluidix GmbH. Print heads and dosing units need to be ordered separately.

5.4 Accessories (can be ordered separately)

Accessories can feature essential methods to improve or support the development of the desired

dosing process or be applied to implement process control.

Possible accessories are listed and explained in the following:

•TopView-camera system including illumination

oimage capturing for observation of processed substrates

odispensing on optically defined positions

ooptical setting of zero point with respect to a substrate or desired area

ooptical adjustment of coordination axes (aligned dosing)

•Stroboscopic system with LED illumination

oqualitative observation of ejected liquid in flight

oqualitative observation of reproducibility of dosing process

oquantitative adjustment of ejected volume

oautocalibration of ejected volume (PipeJet dispenser)

osoftware based storage of images

Manual - BioSpot BT600 workstation

page 9 of 15

•Optical droplet sensor

oonline process control of dosing process by counting ejected droplets

osemi quantitative process control by correlation of generated signals

•Pressure controlled reservoir

oguarantees constant pressure at the dosing nozzle

oimproves long-term stability of the dosing process

oenables big reservoir volumes

opressure support for different (e.g. higher viscous) media

CONSIDER: Accessories must be ordered separately. For more detailed information please

BioFluidix GmbH

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